Temporarily relieves the symptoms of cramps and pains in lower back and legs. Hyland's Leg Cramps with Quinine relieves the symptoms of cramps and pains in the lower back, legs and feet that can disrupt your life. America's #1 OTC leg cramp medicine, Hyland's formula relieves late night charley horse cramps and can be taken day or night without drowsiness. Hyland's Leg Cramps with Quinine is safe to take with other medicines, and has no contraindications and no drug interactions.