Traditionally used for gastrointestinal symptoms, berberine has emerged as a potent 
cardiometabolic aid with diverse benefits and mechanisms of action. It has 
hypoglycemic effects, via both an inhibition of alpha-glucosidase activity and an 
upregulation of insulin receptors in peripheral tissues, thereby improving insulin 
sensitivity.Furthermore, it activates Nrf2, a key regulator of cellular antioxidant 
defense, and attenuates glucose induced neurotoxicity, suggesting a therapeutic 
potential for diabetic neuropathy.

Unique Features:

- Hypoglycemic effects via multiple mechanisms, including enhancement of insulin 
  sensitivity 
- Favorable effects on blood lipids, including a reduction in triglycerides, and both 
  total and LDL cholesterol9
- Activates Nrf-2, a key regulator of antioxidant gene transcription and prevention 
  of glucose-induced neurotoxicity
- Provides 500mg berberine HCl per capsule, the dosing strength used in clinical 
  trials for glucose and lipid control
- Extracted from Berberis vulgaris (European barberry)
  Vegetarian capsule